🏈 Buffalo Bills vs Pittsburgh Steelers betting picks, predictions and odds for their NFL Week 1 showdown on September 12 2021, at 1:00pm ET from Highmark Stadium in Orchard Park, New York. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert NFL betting analysis on this AFC clash between the Bills and Steelers. At the time of posting, the WagerTalk Live Odds screen is showing Buffalo as a -6.5 home favorite over Pittsburgh, with the over/under sitting at 48.5 points.
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